(+/-)-Idazoxan monohydrochloride → Idazoxan
Reaction equation
[CH:1]1[CH:2]=[CH:3][C:4]2[O:10][CH:9]([C:11]3[NH:15][CH2:14][CH2:13][N:12]=3)[CH2:8][O:7][C:5]=2[CH:6]=1.Cl.Cl.N1(C2OC3C=CC=CC=3OC2)CCN=C1>>[CH:1]1[CH:2]=[CH:3][C:4]2[O:10][CH:9]([C:11]3[NH:15][CH2:14][CH2:13][N:12]=3)[CH2:8][O:7][C:5]=2[CH:6]=1Participants
3
Procedure
Idazoxan hydrochloride belongs to the category of α2-adrenoreceptor antagonists. The chemical name of this molecule is 2-(2-imidazolinyl)-1,4-benzodioxane hydrochloride and its molecular formula is C11H12N2O2HCl. Idazoxan is provided in the form of a slightly hygroscopic, white to substantially white powder which is readily soluble in water and methanol and which is soluble to fairly soluble in ethanol.
Sources & evidence
- ORD record
- ord-9081c8a816d442fc86072676bb83cb4c
- Source dataset
- uspto-grants-2009_09
- Patent number
- US07595335B2
Reaction notes
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