HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 4-{1-Ethyl-1-[4-(3-ethyl-3-hydroxy-pent-1-ynyl)-3-methyl-phenyl]-propyl}-2-methyl-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 57849336 | HCID 57849336 | — |
| Product | 4-{1-Ethyl-1-[4-(3-ethyl-3-hydroxy-pent-1-ynyl)-3-methyl-phenyl]-propyl}-2-methyl-benzoic acid | HCID 57849348 | 83.2% |
Reaction Steps
4-{1-Ethyl-1-[4-(3-ethyl-3-hydroxy-pent-1-ynyl)-3-methyl-phenyl]-propyl}-2-methyl-benzoic acid methyl ester (2.20 g, 5.23 mmol) and lithium hydroxide (376 mg, 15.69 mmol) are reacted and purified analogous to Example 1I to give the title compound (1.77 g, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595345B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-15f690a3d907415a970c881f6f321b8d |
| Source note | uspto-grants-2009_09 |