Isocyanate → (4-Isocyanatobutyl)cyclohexane

HRID 736628Notes

Reaction equation

HRID 736628 reaction equation
[N-:1]=[C:2]=[O:3].[CH:4]1([CH2:10][CH2:11][CH2:12][CH2:13]N)[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1>>[N:1]([CH2:13][CH2:12][CH2:11][CH2:10][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1)=[C:2]=[O:3]

Participants

3

Reactant 2

HCID 105034Isocyanate2×HCID 30589564-cyclohexylbutan-1-amine

Product 1

HCID 22590210(4-Isocyanatobutyl)cyclohexaneYield 91%

Procedure

Following the synthetic procedure of 4b′ as described in Example 17, isocyanate 4d′ (91% yield) was synthesized from 4-(cyclohexyl)butylamine as an oil. 1H-NMR (CDCl3) δ0.80-0.95 (m, 2H), 1.10-1.30 (m, 6H), 1.32-1.45 (m, 2H), 1.52-1.75 (m, 7H), 3.28 (t, J=6.6 Hz, 2H).

Sources & evidence

ORD record
ord-43fa33f0591140539a4d93ec59359943
Source dataset
uspto-grants-2009_09
Patent number
US07595403B2

Reaction notes

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