1-[1-(Bromomethyl)cyclopropyl]-4-chlorobenzene → HCID 57850097, compound

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The title compound was prepared from 8-(6-bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9H-purin-6-ylamine and 1-(-bromomethyl-cyclopropyl)-4-chloro-benzene by a procedure similar to examples 1 and 2. The compound was purified by preparative HPLC. 8-(6-Bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-[1-(4-chloro-phenyl)-cyclopropylmethyl]-9H-purin-6-ylamine: 1H NMR (CD3OD) δ 8.24 (s, 1H), 7.24 (d, J=9.3 Hz, 2H), 7.19 (s, 1H), 714 (d, J=8.6 Hz, 2H), 6.93 (s, 1H), 6.08 (s, 2H) 4.49 (s, 2H), 1.41-1.35 (m, 2H), 0.95-0.91 (m, 2H); LC-MS [M+H]+ 531.8.

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