HCID 86590477, compound → HCID 10175070, compound

HRID 736685Notes

Reaction equation

HRID 736685 reaction equation
F[C:2](F)(F)[C:3](O)=O.F[C:9](F)(F)C(O)=O.[CH3:15][C:16]1[CH:25]=[C:24]([CH2:26][O:27][C:28]2[CH:52]=[CH:51][C:31]([C:32]([NH:34][CH2:35][C:36]3([CH:45]4[CH2:50][CH2:49][NH:48][CH2:47][CH2:46]4)[C:41](=[O:42])[NH:40][C:39](=[O:43])[NH:38][C:37]3=[O:44])=[O:33])=[CH:30][CH:29]=2)[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:17]=1>CC(C)=O>[CH:2]([N:48]1[CH2:49][CH2:50][CH:45]([C:36]2([CH2:35][NH:34][C:32](=[O:33])[C:31]3[CH:30]=[CH:29][C:28]([O:27][CH2:26][C:24]4[C:23]5[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=5)[N:17]=[C:16]([CH3:15])[CH:25]=4)=[CH:52][CH:51]=3)[C:37](=[O:44])[NH:38][C:39](=[O:43])[NH:40][C:41]2=[O:42])[CH2:46][CH2:47]1)([CH3:3])[CH3:9]

Participants

3

Reactant 1

HCID 86590477HCID 86590477, compound

Product 1

HCID 10175070HCID 10175070, compoundYield 32.8%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Following the procedure analogous to that used in reaction (9), the compound from Example 29 was reacted with acetone for 5 days to provide the title compound (7 mg, 32.8%). MS found: (M+H)+=558.4.

Sources & evidence

ORD record
ord-1034b0f9aea247578f69f1114d7c5415
Source dataset
uspto-grants-2009_09
Patent number
US07595317B2

Reaction notes

Loading…