Hydroxylamine → HCID 86607873, compound

Participants

Reaction Steps

According to the procedure of Example 17, Steps 4 and 5, 117 mg of tert-butyl cis-4-[({4-[(2-methylquinolin-4-yl)methoxy]phenyl}sulfonyl)amino]-1-prop-2-yn-1-ylpyrrolidine-3-carboxylate, was treated with trifluoroacetic acid, followed by the reaction with hydroxylamine to give 56 mg of cis-N-hydroxy-4-[({4-[(2-methylquinolin-4-yl)methoxy]phenyl}sulfonyl)amino]-1-prop-2-yn-1-ylpyrrolidine-3-carboxamide in 54% yield. MS: 495 2(M+H)+

Provenance & Evidence