Hydroxylamine → HCID 86607882, compound

Participants

Reaction Steps

According to the procedure of Example 24, Step 3, 4-{methyl-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-amino}-tetrahydro-furan-3-carboxylic acid (0.160 g, 0.35 mmol) and hydroxylamine gave (3S,4R)-4-{methyl-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-amino}-tetrahydro-furan-3-carboxylic acid hydroxyamide as an amorphous white solid (0.035 g, 21%) after purification using Biotage Flash 40S chromatography, eluting with 5% methanol in ethyl acetate. MS: 472 (M+H)+

Provenance & Evidence