Formic Acid → HCID 11855598, compound

Participants

Reaction Steps

According to the procedure of Example 29, Step 2, 0.4 g (0.878 mmol) of 4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylamino]-piperidine-3-carboxylic acid hydroxylamine and formic acid gave a mixture of cis- and trans-1-formyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl amino]-piperidine-4-carboxylic acid hydroxyamide as an amorphous white solid (0.035 g, 8%) after reverse phase HPLC (Gilson) on a Phenomex C-18 semi-prep column, eluting with an acetonitrile:water gradient. MS: 499 (M+H)+

Provenance & Evidence