HCID 86607907, compound → HCID 86607909, compound

Participants

Reaction Steps

To a solution of methyl (1R,2R)-2-({[4-(benzyloxy)phenyl]sulfonyl}amino)-1-fluorocyclopentanecarboxylate in EtOAc/CH2Cl2/MeOH (5 mL/2 mL/10 mL) was added 10% Pd/C (0.14 g). The reaction vessel was purged with nitrogen followed by hydrogen. The reaction was stirred for 1 h under 1 atmosphere of hydrogen, and then filtered through celite and concentrated to afford methyl (1R,2R)-1-fluoro-2-{[(4-hydroxyphenyl)sulfonyl]amino}cyclopentanecarboxylate as an amorphous solid (0.433 g, 97%). MS: 318.1 (M+H)+.

Provenance & Evidence