Sodium borohydride → HCID 68817151, compound

Participants

Reaction Steps

A solution of the compound prepared in Example 1 above (1.73 g, 7.10 mmol) in THF (50 mL) was treated with a solution of sodium borohydride (462 mg, 12.2 mmol) in methanol (10 mL). After stirring for 45 min at room temperature, the reaction was quenched by the addition of saturated ammonium chloride (10 mL) and the resulting mixture was extracted with ethyl acetate. The reaction mixture was then concentration, and the residue was purified by flash chromatography to yield the title compound as a colorless oil.

Provenance & Evidence