HCID 10171428, compound → 2-[(4S)-2,2-Dimethyl-1,3-dioxan-4-yl]-2-methylheptan-3-one

Participants

Reaction Steps

24 g (0.1 mol) of (4S)-4-(2-methyl-3-oxo-hept-6-en-2-yl)-2,2-dimethyl-[1,3]dioxane from Example 17 is dissolved in 480 ml of THF. At room temperature, 4.8 g of palladium on carbon (10%) is added. It is hydrogenated at 10 bar of hydrogen for 2 hours until hydrogen absorption is completed. The catalyst is suctioned off, rewashed with THF, and the product is distilled at 95° C./1 mbar. 21 g of product (87% of theory) is obtained.

Provenance & Evidence