Formic Acid → HCID 85968163, compound

HRID 736950Notes

Reaction equation

[NH2:1][C:2]1[C:9]([C:10]([F:13])([F:12])[F:11])=[CH:8][C:5]([C:6]#N)=[CH:4][C:3]=1[C:14]([F:17])([F:16])[F:15].C(O)=[O:19]>>[NH2:1][C:2]1[C:9]([C:10]([F:13])([F:12])[F:11])=[CH:8][C:5]([CH:6]=[O:19])=[CH:4][C:3]=1[C:14]([F:17])([F:16])[F:15]

Participants

Reactant 2

HCID 284Formic Acid

HCID 226251904-Amino-3,5-bis(trifluoromethyl)benzonitrile

Product 1

HCID 85968163HCID 85968163, compound

Procedure

A solution of 5 g (19.67 mmol) 4-amino-3,5-bis-trifluoromethyl-benzonitrile in 30 mL formic acid was shaken in 10 equal portions in pressurised containers for 20 h at 110° C.

Sources & evidence

ORD record: ord-56113f11e2fd4e9fac842a22f851ec1f
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07595312B2

Reaction notes

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