反应详情

温度

140 °C

Palladium on carbon (10%, 410 mg), 100 g of water, 21.8 g of 1,3,5-trichloro-2,4,6-trifluorobenzene and 32.9 g of sodium acetate (4.5 equivalents) were placed in a pressure vessel. After flushing with nitrogen, the pressure vessel was heated to 140° C. and pressurized with 12 bar of hydrogen. A hydrogen pressure of 12 bar was maintained at 140° C. for about 12 hours while stirring vigorously. After cooling to 20-25° C., the pressure vessel was depressurized. The two-phase reaction solution was filtered and the phases were then separated. This gave a yield of 88.2% of 1,3,5-trifluorobenzene.

1. customAfter flushing with nitrogen
2. temperatureA hydrogen pressure of 12 bar was maintained at 140° C. for about 12 hours
3. temperatureAfter cooling to 20-25° C.
4. customThe two-phase reaction solution
5. filtrationwas filtered
6. customthe phases were then separated