HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → Oxane-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 2H-Pyran-4-carboxylic acid, tetrahydro-, methyl ester | HCID 2773520 | — |
| Product | Oxane-4-carboxamide | HCID 13197203 | — |
Reaction Steps
In a 5 L flask, charge methyltetrahydropyran-4-carboxylate (500 ml, 3.75 mol) and concentrated ammonium hydroxide (1.3 L) and stir the reaction at room temperature for 48 hours. Filter the reaction and dry the white solid in a vacuum oven at 60° C. overnight. to obtained 36.33 g white solid of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595339B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-39570718d46849cca3f4a1cbf5eedf77 |
| Source note | uspto-grants-2009_09 |