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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 737080Generated: October 26, 2026

Potassium Carbonate → 4-(3-Bromo-benzyl)-2-phenyl-morpholine

https://huagongshe.com/reaction/737080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant3-Bromobenzyl bromideHCID 69979—
Reactant2-PhenylmorpholineHCID 91101—
SolventAcetonitrileHCID 6342—
Product4-(3-Bromo-benzyl)-2-phenyl-morpholineHCID 5784949565%

Reaction Steps

1.877 g of 3-Bromobenzyl bromide and 1 g of 2-Phenyl-morpholine in 15 mL of acetonitrile were stirred at room temperature and 2.076 g of potassium carbonate was added. The reaction was stirred at room temperature overnight. The solution was filtered through Celite and concentrated in vacuo to afford a brown solid. Purification by flash chromatography afforded 1.073 g of product. 65% yield ES MS m/z 332

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07595397B2
Source datasetuspto-grants-2009_09
ORD IDord-d683687a9ee24236882084116cd19dda
Source noteuspto-grants-2009_09