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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 737082Generated: October 26, 2026

Potassium Carbonate → 4-(2-Bromo-benzyl)-2-phenyl-morpholine

https://huagongshe.com/reaction/737082

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-Bromobenzyl bromideHCID 76965—
Reactant2-PhenylmorpholineHCID 91101—
SolventAcetonitrileHCID 6342—
Product4-(2-Bromo-benzyl)-2-phenyl-morpholineHCID 5784954663%

Reaction Steps

1.877 g of 2-Bromobenzyl bromide and 1 g of 2-Phenyl-morpholine in 15 mL of acetonitrile were stirred at room temperature and 2.076 g of potassium carbonate was added. The reaction was stirred at room temperature overnight. The solution was filtered through Celite and concentrated in vacuo to afford a brown solid. Purification by flash chromatography afforded 1.052 g of product. 63% yield ES MS m/z 332

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07595397B2
Source datasetuspto-grants-2009_09
ORD IDord-530bcc1a9f944625a2b1a66bc30c021d
Source noteuspto-grants-2009_09