HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylamine → HCID 57849752, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylamine | HCID 2906 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 86616438 | HCID 86616438 | — |
| Product | HCID 57849752 | HCID 57849752 | — |
Reaction Steps
From (S)-2-[5-(4-Carboxy-phenyl)-thiazol-2-ylcarbamoyl]-pyrrolidine-1-carboxylic acid benzyl ester (Compound 5353, example 353, 0.03 g, 0.07 mmol), HATU (0.033 g, 0.086 mmol), and (0.03 mL, 0.26 mmol) of cyclopentylamine using General Procedure 3F. 1HNMR (DMSO-d6) δ(ppm)12.42 (m, 0.7H), 8.30-8.27 (d, 1H), 7.80-7.11 (m, 10H), 5.06-4.89 (m, 2 H), 4.50 (m, 1H), 3.51-3.48 (m, 1H), 2.26 (m, 1H), 1.89-1.52 (m, 9H), 1.14 (s, 1H); MS: 519.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07595398B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-caa4cd221c0e49b6bf76cdcc8869ce8f |
| Source note | uspto-grants-2009_09 |