HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 737458Generated: October 30, 2026
p-Toluidine → 4-Methoxy-4'-methyldiphenylamine
https://huagongshe.com/reaction/737458
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 4-Chloroanisole | HCID 12167 | — |
| Reagent | Isoxazole, 5-phenyl- | HCID 136800 | — |
| Reagent | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| Catalyst | HCID 178439023 | HCID 178439023 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 4-Methoxy-4'-methyldiphenylamine | HCID 11435828 | 0.656% |
Reaction Steps
These solutions were added to a 384-
well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose
each of these solutions (200 nL each) into a 1536-well plate.
Provenance & Evidence
| DOI | 10.1126/science.aar5169 |
|---|
| Source dataset | Ahneman |
|---|
| ORD ID | ord-d5e0cb3984884e1284e198f125f6dd58 |
|---|
| Source note | Ahneman |
|---|
