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HRID73753

反应详情

EQUATION

反应方程式

HRID 73753 的结构方程式

REACTANTS

反应物

2
结构：OC[C@H]1CCNC1
HCID7446911

(S)-PYRROLIDIN-3-YLMETHANOL

C5H11NO

结构：O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(Br)c1
HCID72546089

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CC[C@H](CO)C2)c(Br)c1
HCID86702603

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in an analogous fashion to that described in Stage 9.2 using 5-bromo-6-chloro-N-(4-(chlorodifluoromethoxy)phenyl)nicotinamide (Stage 9.3) and (S)-1-pyrrolidin-3-yl-methanol to afford an off-white crystalline solid. HPLC (Condition 4) tR5.82 min, UPLC-MS (Condition 3) tR=1.14 min, m/z=476.2/478.3 [M+H]+.

WORKUP

后处理

  1. customto afford an off-white crystalline solid