HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 737751Generated: October 29, 2026
p-Toluidine → 2-Pyridinamine, N-(4-methylphenyl)-
https://huagongshe.com/reaction/737751
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Iodopyridine | HCID 221126 | — |
| Reagent | Ethyl 5-methylisoxazole-3-carboxylate | HCID 76677 | — |
| Reagent | 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | HCID 123583 | — |
| Catalyst | HCID 178492620 | HCID 178492620 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Pyridinamine, N-(4-methylphenyl)- | HCID 2786419 | 98.177% |
Reaction Steps
These solutions were added to a 384-
well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose
each of these solutions (200 nL each) into a 1536-well plate.
Provenance & Evidence
| DOI | 10.1126/science.aar5169 |
|---|
| Source dataset | Ahneman |
|---|
| ORD ID | ord-c46abc083b374c05a6b5e52cfe026d89 |
|---|
| Source note | Ahneman |
|---|