HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-6-chloropyridine-3-carboxylic acid → 5-bromo-6-chloro-N-(4-(perfluoroethoxy)phenyl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| Reactant | 4-(Pentafluoroethoxy)aniline | HCID 12328719 | — |
| Product | 5-bromo-6-chloro-N-(4-(perfluoroethoxy)phenyl)nicotinamide | HCID 86702620 | — |
Reaction Steps
The title compound was prepared in an analogous fashion to that described in Stage 9.3 using 5-bromo-6-chloro-nicotinic acid and 4-(perfluoroethoxy)aniline to afford an off-white crystalline solid. HPLC (Condition 4) tR=6.73 min, UPLC-MS (Condition 3) tR=1.30 min, m/z=443.1 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829195B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-9cd77a866ae34b0c9f90ca13a7d7513f |
| Source note | uspto-grants-2014_09 |