HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chlorodifluoromethoxy)aniline → 6-chloro-N-(4-(chlorodifluoromethoxy)phenyl)-5-iodonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chlorodifluoromethoxy)aniline | HCID 572793 | — |
| Reactant | 6-Chloro-5-iodonicotinic acid | HCID 22271477 | — |
| Product | 6-chloro-N-(4-(chlorodifluoromethoxy)phenyl)-5-iodonicotinamide | HCID 86702626 | — |
Reaction Steps
The title compound was prepared in an analogous fashion to that described in Stage 11.2 using 6-chloro-5-iodonicotinic acid and 4-(chlorodifluoromethoxy)aniline to afford an off-white powder. HPLC (Condition 4) tR=6.47 min, UPLC-MS (Condition 3) tR=1.26 min, m/z=456.8 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829195B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-f324f55a49224e8a8e5a5fed04932a04 |
| Source note | uspto-grants-2014_09 |