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HRID73804

反应详情

EQUATION

反应方程式

HRID 73804 的结构方程式

REACTANTS

反应物

2
结构：O[C@@H]1CCNC1
HCID2759337

(R)-3-Hydroxypyrrolidine

C4H9NO

结构：O=C(Nc1ccc(SC(F)(F)F)nc1)c1cnc(Cl)c(Br)c1
HCID86702634

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Nc1ccc(SC(F)(F)F)nc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1
HCID86702633

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in an analogous fashion to that described in Stage 8.1 using 5-bromo-6-chloro-N-(6-((trifluoromethyl)thio)pyridin-3-yl)nicotinamide (Stage 32.2) and (R)-pyrrolidin-3-ol to afford an off-white powder. HPLC (Condition 4) tR=5.53 min, UPLC-MS (Condition 3) tR=1.01 min, m/z=463.1 [M+H]+.

WORKUP

后处理

  1. customto afford an off-white powder