HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → Methyl 1-(4-methoxybenzamido)cyclohexane-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | Methyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 22645079 | — |
| Product | Methyl 1-(4-methoxybenzamido)cyclohexane-1-carboxylate | HCID 32468563 | 71% |
Reaction Steps
581 mg (3 mmol) of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid phenylmethyl ester, and 512 mg (3 mmol) of 4-methoxybenzoyl chloride was used instead of phenylacetyl chloride in the process according to Reference Example 1 to obtain 619 mg (71%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829209B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-2dde8241bbcb427b9a110f37403ccdef |
| Source note | uspto-grants-2014_09 |