HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-2-thenoyl Chloride → 1-[[(3-Methyl-2-thienyl)carbonyl]amino]cyclohexanecarboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-2-thenoyl Chloride | HCID 2737605 | — |
| Reactant | Methyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 22645079 | — |
| Product | 1-[[(3-Methyl-2-thienyl)carbonyl]amino]cyclohexanecarboxylic acid methyl ester | HCID 32468521 | 47% |
Reaction Steps
581 mg (3 mmol) of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid phenylmethyl ester, and 482 mg (3 mmol) of 3-methyl-2-thiophenecarbonyl chloride was used instead of phenylacetyl chloride in the process according to Reference Example 1 to obtain 394 mg (47%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829209B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-115d9aa10ec54874a1d6b746c5951c72 |
| Source note | uspto-grants-2014_09 |