HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 738539Generated: October 28, 2026
p-Toluidine → 2-Pyridinamine, N-(4-methylphenyl)-
https://huagongshe.com/reaction/738539
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Iodopyridine | HCID 221126 | — |
| Reagent | Isoxazole, 3-phenyl- | HCID 136798 | — |
| Reagent | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| Catalyst | HCID 178492609 | HCID 178492609 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Pyridinamine, N-(4-methylphenyl)- | HCID 2786419 | 69.841% |
Reaction Steps
These solutions were added to a 384-
well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose
each of these solutions (200 nL each) into a 1536-well plate.
Provenance & Evidence
| DOI | 10.1126/science.aar5169 |
|---|
| Source dataset | Ahneman |
|---|
| ORD ID | ord-c8f6c3502a0d4421b3beff07f476497f |
|---|
| Source note | Ahneman |
|---|
