HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 738986Generated: November 1, 2026
p-Toluidine → 2-Pyridinamine, N-(4-methylphenyl)-
https://huagongshe.com/reaction/738986
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Chloropyridine | HCID 7977 | — |
| Reagent | Methyl isoxazole-5-carboxylate | HCID 2736892 | — |
| Reagent | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| Catalyst | HCID 178439023 | HCID 178439023 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Pyridinamine, N-(4-methylphenyl)- | HCID 2786419 | 38.11% |
Reaction Steps
These solutions were added to a 384-
well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose
each of these solutions (200 nL each) into a 1536-well plate.
Provenance & Evidence
| DOI | 10.1126/science.aar5169 |
|---|
| Source dataset | Ahneman |
|---|
| ORD ID | ord-7c3a2824f08e47468356d708336ee404 |
|---|
| Source note | Ahneman |
|---|
