HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl iodoacetate → (6-Amino-1H-indol-3-yl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl iodoacetate | HCID 12183 | — |
| Reactant | 6-Nitro-1H-indole | HCID 78502 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (6-Amino-1H-indol-3-yl)-acetic acid ethyl ester | HCID 66675483 | — |
Reaction Steps
(6-Amino-1H-indol-3-yl)-acetic acid ethyl ester (B-17) was synthesized following the general scheme above starting from 6-nitroindole and iodo-acetic acid ethyl ester. Overall yield (24%). HPLC ret. time 0.95 min, 10-99% CH3CN, 5 min run; ESI-MS 219.2 m/z (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829204B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-ed116ac2db13497eaec502a4321fada4 |
| Source note | uspto-grants-2014_09 |