HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide dimethyl acetal → 5-(2-Dimethylamino-vinyl)-2,4-dinitro-benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | Ethyl 5-methyl-2,4-dinitrobenzoate | HCID 15184632 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-(2-Dimethylamino-vinyl)-2,4-dinitro-benzoic acid ethyl ester | HCID 85197281 | 32.3% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A mixture of 5-methyl-2,4-dinitro-benzoic acid ethyl ester (39 g, 0.15 mol) and dimethoxymethyl-dimethylamine (32 g, 0.27 mol) in DMF (200 mL) was heated at 100° C. for 5 h. The mixture was poured into ice water. The precipitate was collected via filtration and washed with water to afford 5-(2-dimethylamino-vinyl)-2,4-dinitro-benzoic acid ethyl ester (15 g, 28%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829204B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-926eda6f61cd48d99f432d53abf418bf |
| Source note | uspto-grants-2014_09 |