HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 740713Generated: October 28, 2026
p-Toluidine → 2-Pyridinamine, N-(4-methylphenyl)-
https://huagongshe.com/reaction/740713
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Iodopyridine | HCID 221126 | — |
| Reagent | 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | HCID 123583 | — |
| Reagent | Isoxazole, 3-methyl-5-phenyl- | HCID 136804 | — |
| Catalyst | HCID 178492609 | HCID 178492609 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Pyridinamine, N-(4-methylphenyl)- | HCID 2786419 | 90.644% |
Reaction Steps
These solutions were added to a 384-
well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose
each of these solutions (200 nL each) into a 1536-well plate.
Provenance & Evidence
| DOI | 10.1126/science.aar5169 |
|---|
| Source dataset | Ahneman |
|---|
| ORD ID | ord-013a076dff2344ff9b697c4c6674e134 |
|---|
| Source note | Ahneman |
|---|
