Acetone → Propane-1,2,3-triol;propan-2-one
Reaction equation
[CH3:1][C:2]([CH3:4])=[O:3].[OH:5][CH2:6][CH:7]([CH2:9][OH:10])[OH:8]>[Pd]>[CH3:1][C:2]([CH3:4])=[O:3].[OH:5][CH2:6][CH:7]([CH2:9][OH:10])[OH:8]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 200 °C
Procedure
Acetone (5.81 g, 7.34 ml, 0.1 mol), glycerol (92.09 g, 73.7 ml, 1 mol), and 10% Pd/C (5 wt %, 0.29 g) are charged to a Parr reactor, purged with nitrogen, heated to 200° C. with stirring and run at 1000 psi of hydrogen for 4 hrs. GC analysis reveals complete consumption of acetone and shows presence of glycerol monoether 3-isopropoxy-1,2-propanediol (78.5%), glycerol diethers 1,3-di-isopropoxy-2-propanol and 2,3-di-isopropoxy-1-propanol (3.9%), iso-propanol+acetone (7.2%).
Workup
- custompurged with nitrogen
- customconsumption of acetone
Sources & evidence
- ORD record
- ord-2d585071d7f44f4895078fba8e2aa2ed
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08829229B2
Reaction notes
Loading…