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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 74144Generated: October 26, 2026

Ammonia → Isophorone diamine

https://huagongshe.com/reaction/74144

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantIsophorone diamineHCID 17857—
Reactant3-Cyano-3,5,5-trimethylcyclohexanoneHCID 99068—
ProductIsophorone diamineHCID 17857—
Product3-Cyano-3,5,5-trimethylcyclohexylamineHCID 21694456—

Reaction Steps

3-Aminomethyl-3,5,5-trimethylcyclohexylamine (i.e., isophoronediamine, abbreviated as IPDA) is used as a starting material for preparing substances such as 3-isocyanatomethylene-3,5,5-trimethylcyclohexyl isocyanate (i.e., isophorone diisocyanate, abbreviated as IPDI) or polyamides, and also used as a curing agent for epoxy resins. 3-Aminomethyl-3,5,5-trimethylcyclohexylamine is prepared, on an industrial scale, by reacting 3-cyano-3,5,5-trimethylcyclohexanone (i.e., isophoronenitrile, abbreviated as IPN) with ammonia to form 3-cyano-3,5,5-trimethylcyclohexylamine (i.e., isophoronenitrilimine, abbreviated as IPNI), followed by a reductive amination reaction of IPNI with hydrogen in the presence of ammonia in a catalytic way. The above reaction processes are as follows:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829245B2
Source datasetuspto-grants-2014_09
ORD IDord-8e8900f9242844e7b85115ed9dba1080
Source noteuspto-grants-2014_09