反应详情

eq-2-Hydroxymethylquinolizidine (N. J. Leonard et al, J. Org. Chem,1957, 22, 1445) was reacted with the acid chloride of 1-n-propylindole-3-carboxylic acid using the method of Example 1. The product was chromatographed on silica gel eluting with ethyl acetate. The resulting yellow oil was crystallised from n-pentane to afford the title compound (E17) as a white solid mp 75°-76° C.

1. customThe product was chromatographed on silica gel eluting with ethyl acetate
2. customThe resulting yellow oil was crystallised from n-pentane