HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexane, (bromomethyl)- → HCID 131719530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexane, (bromomethyl)- | HCID 137636 | — |
| Reactant | Quinolizidin-2-ylmethylindole-3-carboxylate | HCID 131719520 | — |
| Product | HCID 131719530 | HCID 131719530 | — |
Reaction Steps
eq-Quinolizidin-2-ylmethyl indole-3-carboxylate (E9b) was alkylated with cyclohexylmethyl bromide using the method of Example 18. The product was chromatographed on silica gel eluting initially with ether, then with ethyl acetate, to afford a colourless oil, which crystallised from n-pentane to give the title compound (E29) as a white solid mp 98°-100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05552398 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-3061b805d53746fe9cd307299a55a4af |
| Source note | uspto-grants-1996_09 |