HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 131719531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Quinolizidin-2-ylmethylindole-3-carboxylate | HCID 131719520 | — |
| Product | HCID 131719531 | HCID 131719531 | — |
Reaction Steps
eq-Quinolizidin-2-ylmethyl indole-3-carboxylate (E9b) was acylated with acetyl chloride using the method of Example 18. The product was chromatographed on silica gel eluting with ethyl acetate to give a pale yellow oil, which crystallised from ether to afford the title compound (E30) as a white solid mp 127°-129° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05552398 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-d30c67c3010b4537a219f259929b6072 |
| Source note | uspto-grants-1996_09 |