反应详情

To a cold (0° C.) solution of the product of step 2 (5.45 g, 18.5 mmol) in CH2C2 (350 mL) was added PCC (6.13 g, 28 mmol). The mixture was stirred at r.t. for 6.5 h and filtered through a short pad of silica gel (eluted with acetone). The eluant was concentrated and the residue was chromatographed on silica gel (eluted with 30 % EtOAc/CH2Cl2) to give 5.2 g of the title compound.

1. filtrationfiltered through a short pad of silica gel (eluted with acetone)
2. concentrationThe eluant was concentrated
3. customthe residue was chromatographed on silica gel (eluted with 30 % EtOAc/CH2Cl2)