HCID 19426838, compound → HCID 67732574, compound

Participants

Reaction Steps

A mixture of the product of Step 2, above (14, 2.0 g, 6.8 mmol) and 5% Pd/BaSO4 (200 mg) in methanol was subjected to hydrogenation at atmospheric pressure. After the absorption of the required amount of hydrogen, the suspension was filtered and washed with methanol. Methanol was evaporated from the filtrate. The residue was purified by column chromatography on silica gel (eluent=ethyl acetate:n-hexane, 1:4) to give 1.8 g (95% yield) of the title compound as pale yellow solids.

Provenance & Evidence