Water → HCID 54454034, compound

Participants

Reaction Steps

3- (2-Dimethylaminomethyleneaminoimidazol-1-yl)-N-(benzyloxycarbonyl)-L-alanine methyl ester (937 mg) was dissolved in methanol (25 ml), and 50% water-containing 10% Pd/C (468 mg) was added. Then, the mixture was vigorously stirred for 2 hours under an atmosphere of hydrogen. The catalyst was filtered off. The solvent was evaporated under reduced pressure. The resulting residue was purified by silica gel flush column chromatography (eluent: 7% ammonia-containing ethanol-chloroform a 3:97) to give the title compound (482 mg).

Provenance & Evidence