HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-N,N-dimethylethylamine → 1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[2-(N,N-dimethylamino)ethoxy]benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| Reactant | 1-(2-Trifluoromethylbenzyl)-2-(3-methylphenyl)-6-hydroxybenzimidazole | HCID 19353988 | — |
| Product | 1-(2-trifluoromethylbenzyl)-2-(3-methylphenyl)-6-[2-(N,N-dimethylamino)ethoxy]benzimidazole | HCID 19354009 | — |
Reaction Steps
The title compound was prepared essentially as described in Example 107 except that the compound of Example 120 was reacted with 2-(N,N-dimethylamino)ethyl chloride. mp 93° C., NMR, IR, MS 453.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05552426 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-a08b0e986de0479581486c1608970cae |
| Source note | uspto-grants-1996_09 |