Acetic Acid → HCID 19427054, compound

Participants

Reaction Steps

A mixture of 3-ethylaniline (1.0 g, 8.25 mmol), triethyl orthoacetate (0.670 g, 4.13 mmol) and glacial acetic acid (0.019 ml, 0.33 mmol) was heated to reflux in an oil bath at 125°-140° C. for 3 hr. It was purified by flash chromatography on silica gel and the product was then crystallized from pet-ether-dichloromethane to give the title compound (0.770 g, 72%) as an off-white soft crystal. Mp 86°-87° C.

Provenance & Evidence