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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 741815Generated: October 26, 2026

Ethyl ketone → 3-[1-Hydroxy-1-(thiazol-2-yl)propyl]benzyl alcohol

https://huagongshe.com/reaction/741815

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl ketoneHCID 7288—
ReactantThiophenolHCID 7969—
Reactant1-Bromo-3-(3,4-dimethoxybenzyloxy)-5-fluorobenzeneHCID 19426985—
Reactant1-(Thiazol-2-yl)propanoneHCID 23179914—
Product3-[1-Hydroxy-1-(thiazol-2-yl)propyl]benzyl alcoholHCID 54165288—

Reaction Steps

Following the procedure described for Phenol 2, Step 2 and for Phenol 7, Step 3 but substituting the compound from Step 1 for 1-bromo-3-(3,4-dimethoxybenzyloxy)-5-fluorobenzene and 1-(thiazol-2-yl)propanone (from Phenol 1, Step 2) for 3-pentanone the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05552437
Source datasetuspto-grants-1996_09
ORD IDord-bfebb7870b764f9194de59381280bb02
Source noteuspto-grants-1996_09