HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl ketone → 6-[1-Hydroxy-1-(thiazol-2-yl)propyl]pyridin-2-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl ketone | HCID 7288 | — |
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | 1-(Thiazol-2-yl)propanone | HCID 23179914 | — |
| Reactant | 2-Bromo-6-(tert-butyldiphenylsiloxy)methylpyridine | HCID 23370237 | — |
| Product | 6-[1-Hydroxy-1-(thiazol-2-yl)propyl]pyridin-2-methanol | HCID 19426946 | — |
Reaction Steps
Following the procedure described for Phenol 2, Step 2 and for Phenol 7, Step 3 but substituting 6-bromo(O-tert-butyldiphenylsilyl)pyridin-2-ylmethanol (from Alcohol 2, Step 4) for 1-bromo-3-(3,4-dimethoxy)benzyloxy-5-fluorobenzene and 1-(thiazol-2-yl)propanone (from Phenol 1, Step 2) for 3-pentanone the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05552437 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-694b6b26e42d496e9e65e7b39222151b |
| Source note | uspto-grants-1996_09 |