Azobisisobutyronitrile → HCID 23370213, compound

Participants

Reaction Steps

To a solution of 2-cyano-4-(furan-3-yl)-7-methylquinoline (4.2 g) in refluxing CCl4 (400 mL) was added NBS (3.3 g) and AIBN (150 mg) portionwise. After 90 min., the mixture was cooled to r.t. filtered through a pad of silica gel washing with CH2Cl2. The filtrate was concentrated and swished with Et2O for 15 h. The solid precipitate was collected and was 85% of the title compound. This material was used as such in the subsequent reactions.

Provenance & Evidence