Ethylenediamine → HCID 21479583, compound

Participants

Reaction Conditions

Reaction Steps

19 parts of cyanuric chloride are stirred vigorously into 50 parts of water, with addition of a wetting agent and 5 parts of disodium hydrogen phosphate, at a temperature of 0° C. A neutral solution of 53 parts of 1-amino-4-(3-amino-2,4,6-trimethyl-5-sulfophenyl)anthraquinone-2-sulfonic acid in 450 parts of water is added dropwise; during this procedure, the pH is kept at a value of 4.5 by addition of sodium hydroxide solution. When the reaction has ended, 6 parts of ethylenediamine in 54 parts of water are added dropwise such that the temperature remains below 15° C. and the pH remains at a value of 7. The pH is then increased to and kept at a value of 8.5. To bring the conversion to completion, the mixture is heated to a temperature of 40° C. towards the end of the reaction. A solution of 1-amino-4-{3-[(2-aminoethylamino)-6-chloro- 1,3,5-triazin-2-ylamino]-2,4,6-trimethyl-5-sulfophenyl}anthraquinone-2-sulfonic acid (solution 1) is obtained.

Provenance & Evidence