HCID 178419121, compound → (R)-(-)-1,2,3,4-Tetrahydro-1-naphthol

HRID 741877Notes

Reaction equation

HRID 741877 reaction equation
C1(N2B[C@H:10]([C:12]3[CH:17]=CC=CC=3)[C@@H:9]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[O:8]2)C=CC=CC=1.C1([C@@H]2[C@@H](C3C=CC=CC=3)ON(C)B2)C=CC=CC=1>>[C@H:9]1([OH:8])[C:18]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:17][CH2:12][CH2:10]1

Participants

3

Reactant 2

HCID 178419121HCID 178419121, compoundHCID 178479844HCID 178479844, compound

Product 1

HCID 7058028(R)-(-)-1,2,3,4-Tetrahydro-1-naphthol

Procedure

Using substantially the same procedure as recited in Example 4 but substituting the title compound of Example 2 for the title compound of Example 1, the title compound of Example 12 was prepared in 88% e.e.

Sources & evidence

ORD record
ord-9c40be5379774da8bf9a0913d961dc1d
Source dataset
uspto-grants-1996_09
Patent number
US05552548

Reaction notes

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