Triethylamine → 3-(Indan-5-yl)-1-methyl-2-thioxo-imidazolidin-4-one

Participants

Reaction Steps

The title compound was prepared by the procedure described in Example 1 using 7.7 g of indan-5-yl-isothiocyanate, 6.7 g of sarcosine ethyl ester hydrochloride, 12 g of triethyl amine, and 300 mL of chloroform. Crystallization from ethyl acetate afforded the title compound (7.9 g) as a tan solid, m.p. 158-160° C. Anal. Calcd. for C13H14N2O S: C, 63.39; H, 5.73; N,11.37. Found: C, 63.30; H, 5.81; N, 11.31. Mass spectrum (EI, M.+) m/z 246.

Provenance & Evidence