反应详情

To a methanol (5 mL) solution of 2-(2-(2-phenylethyl)aminoanilin-5-yl)benzoxazole (see Working Example 52-1) (140 mg, 0.425 mmol) was added 1,1,1-trimethoxyethane (61.3 mg, 0.510 mmol), and this was stirred at room temperature for 6 hours. After the reaction was complete, this was concentrated, and the residue obtained was purified by silica gel column chromatography to yield the title compound (98.4 mg, 66% yield) as white crystals.

1. concentrationthis was concentrated
2. customthe residue obtained
3. customwas purified by silica gel column chromatography