154594-22-6 → 3-(1-Methyl-3-pyrrolidinyl)-5-(4H-1,2,4-triazol-4-yl)-1H-indole

HRID 742323Notes

Reaction equation

HRID 742323 reaction equation
C[N:2]1[CH2:7][CH2:6][CH:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([N:17]4[CH:21]=[N:20][N:19]=[CH:18]4)[CH:15]=3)[NH:10][CH:9]=2)[CH2:4][CH2:3]1.CN(CCC1C2C(=CC=C(N3C=NN=C3)C=2)NC=1)C>>[CH3:7][N:2]1[CH2:3][CH2:4][CH:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([N:17]4[CH:21]=[N:20][N:19]=[CH:18]4)[CH:15]=3)[NH:10][CH:9]=2)[CH2:6]1

Participants

3

Reactant 2

HCID 9881526154594-22-6HCID 10333932HCID 10333932, compound

Product 1

HCID 102210023-(1-Methyl-3-pyrrolidinyl)-5-(4H-1,2,4-triazol-4-yl)-1H-indole

Procedure

3(R)-N-methyl-3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]pyrrolidine of formula IA: ##STR3## 3(S)-N-methyl-3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl-]pyrrolidine of formula IB: ##STR4## N-methyl-4-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]piperidine of formula IC: ##STR5## N,N-dimethyl-2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethylamine of formula ID: ##STR6## and salts and prodrugs thereof.

Sources & evidence

ORD record
ord-9ddff1c09a9b4f38899793caaf2248a8
Source dataset
uspto-grants-1996_09
Patent number
US05554629

Reaction notes

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