Bromide ion → Benzo[b]quinolizinium hexafluorophosphate

Participants

Reaction Steps

Benzo[b]quinolizinium bromide (508.5 g, 1.95 mol) was dissolved in 5 L of distilled water with heating (steam-bath). Potassium hexafluorophosphate (367.2 g, 1.95 mol) was dissolved in 1.1 L of water with heating and the resulting solution was poured in portions into the above bromide solution with steam-bath heating (20 min). The precipitate was formed immediately and the mixture was stirred at room temperature for 3 h, then stirred 1 h in an ice-water bath. The solid was filtered, washed with cold water (800 mL), dried (50°-60° C.) in vacuo for 3 days to afford 601 g (94.8%) of benzo[b]quinolizinium hexafluorophosphate. (Formula lI: R1 =R2 =R7 =H; X- --=PF6-).

Provenance & Evidence