3-Bromofuran → HCID 19047590, compound

Participants

Reaction Steps

To a mixture of 3-(3-acetyloxy-l-propynyl)furan (1.44 g, 8.7 mmol), 3-bromofuran (2.55 g, 0.017 mol), and Pd(P(C6H5)3)4 (1.0 g, 0.8 mmol) in THF was added added zinc chloride (0.5M in THF, 34 ml, 0.017 mol) and the mixture was stirred at room temperature for 4 hours. The reaction mixture was concentrated in vacuo and the residue was purified by silica column chromatography (methylene chloride/hexane, 2:1) to afford 1.25 g (85%) of [1,1-di(3-furyl)]-1,2-propadiene (Formula III: R3 and R4 together form =CH2 ; R5 =R6 =3-furanyl) as a pale yellow oil.

Provenance & Evidence